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Persönliche Homepage von Dr. Klaus Fließbach


Personal data:

Married with Maria Fließbach, three children (Ada, Paul and Johanna)

 

Education and working experience

1992-1999

 

 

Psychology at the Universities of Gießen and Bonn
(Diploma 1999)

1995-2002

 

 

Medicine at the University of Bonn (M.D. 2002)

2003

 

 

Dr. med. (Supervisor Prof. U. Schlegel, Dep. of Neurology,
University of Bonn)

2003-2004

 

 

Assistant Doctor at the Dep. of Neurology, University of Bonn
(Prof. T. Klockgether)

2004-now

 

 

Assistant Doctor at the Dep. of Epileptology, University of Bonn
(Prof. C.E. Elger)

2005-now

 

 

Scientific fellow in the group NeuroCognition-Imaging,
Life&Brain Center, Bonn

2007

6 months clinical training in neurological intensive care at the Dep. of Neurosurgery, University of Bonn (Prof. Dr. J. Schramm)

2010-now

Scientific fellow at the Center for Economics and Neuroscience (CENs), University of Bonn

Grants:

Two years grant for the project "Neurobiological foundations of social preferences" by Deutsche Forschungsgemeinschaft (FL 715/1-1), starting April 2010.

 

Research interests:

Functional imaging of the human reward system

The neurobiological foundations of social preferences

Material and task-specificity in episodic memory encoding

Neuropsychological assessment of cognitive side effects of neurological treatments

 

 

  

Functional imaging of the human reward system


Rohe T., Weber B., Fliessbach K. Dissociation of BOLD Responses to Reward Prediction Error and Reward Value by a Model Comparison. Under review.

Fliessbach K., Rohe T., Linder N.S., Trautner P., Elger C.E., Weber B. Retest Reliability of Reward Related BOLD Signals. Neuroimage. 2010 Apr 15;50(3):1168-76.

 

The neurobiological foundations of social preferences


Fliessbach K., Phillipps C.B., Trautner P., Schnabel M., Elger C.E., Falk A., Weber B. Neural responses to violations of the Equity principle. Under review.


Kuss K., Falk A., Trautner P., Elger C.E., Weber B., Fliessbach K. A reward prediction error for charitable donations reveals outcome orientation of donators. Social Cog Affect Neuroscience. Accepted for Publication.


Dohmen T; Falk A.; Fliessbach K; Sunde U.; Weber B. Relative versus absolute income, joy of winning, and gender: Brain imaging evidence. J Pub Economics, 2011, 95(3-4): 279-85  


Fliessbach K. Soziale Präferenzen. In: Neuroökonomie. Grundlagen - Methoden - Anwendungen. (Reimann M., Weber B. (eds)). Wiesbaden: Gabler Verlag. 2011. 


Fliessbach K., Weber B., Trautner P., Dohmen T., Sunde U., Elger C.E., Falk A. Social comparison affects reward-related brain activity in the human ventral striatum. Science. 2007 Nov 23;318(5854):1305-8.

 

Material and task-specificity in episodic memory encoding


Fliessbach K., Witt J.-A., Packheiser J., von Lehe, M., Elger C.E., Helmstaedter C. Depth-of-processing effects on memory encoding after selective amygdalo-hippocampectomy. Behav Brain Res. 2011 Jan 1;216(1):402-7.


Fliessbach K., Buerger C., Trautner P., Elger C.E., Weber B. Differential effects of semantic processing on memory encoding. Hum Brain Mapp. 2010 Nov;31(11):1653-64.


Weber B., Fliessbach K., Lange N., Kügler F., Elger C.E. Material specific memory processing is related to language dominance. Neuroimage. 2007 Aug 15;37(2):611-7.


Fliessbach K., Trautner P., Quesada C.M., Elger C.E., Weber B. Cerebellar contributions to episodic memory encoding as revealed by fMRI. Neuroimage. 2007 Apr 15;35(3):1330-7.


Fliessbach K., Weis S., Klaver P., Elger C.E., Weber B. The effect of word concreteness on recognition memory. Neuroimage. 2006 Sep;32(3):1413-21.

 

Neuropsychological assessment of cognitive side effects of neurological treatments


Fliessbach, K*. Rogowski*, Hoppe C., Sabel, M; Goeppert M.; Helmstaedter C., Calabrese P.,  Schackert G., Tonn JC. MD, Simon M., Schlegel U. for the German Glioma Network. Computer-based assessment of cognitive function after brain tumor therapy: validation of NeuroCogFX® in brain tumor patients. J Neurooncol. 2010 Dec;100(3):427-37. *gemeinsame Erstautorenschaft 


Juergens A., Pels H., Rogowski S., Fliessbach K., Glasmacher A., Engert A., Reiser M., Diehl V., Vogt-Schaden M., Egerer G., Schackert G., Reichmann H., Kroschinsky F., Bode U., Herrlinger U., Linnebank M., Deckert M., Fimmers R., Schmidt-Wolf I., Schlegel U. Longterm survival without cognitive compromises after chemotherapy in primary CNS lymphoma. Ann Neurol. 2010 Feb;67(2):182-9.


Hoppe C, Fliessbach K, Schlegel U, Elger CE, Helmstaedter C. NeuroCog FX: computerized screening of cognitive functions in patients with epilepsy. Epilepsy Behav. 2009 Oct;16(2):298-310.


Fliessbach K., Hoppe C., Schlegel U., Elger C.E., Helmstaedter C. NeuroCogFX - eine computergestützte neuropsychologische Testbatterie für Verlaufsuntersuchungen bei neurologischen Erkrankungen. Fortschr Neurol Psychiatr. 2006 Nov;74(11):643-50.


Fliessbach K., Helmstaedter C., Urbach H., Althaus A., Pels H., Linnebank M., Juergens A., Glasmacher A., Schmidt-Wolf I.G., Klockgether T., Schlegel U. Neuropsychological outcome after chemotherapy for primary CNS lymphoma: a prospective study. Neurology. 2005 Apr 12;64(7):1184-8.


Fliessbach K., Urbach H., Helmstaedter C., Pels H., Glasmacher A., Kraus J.A., Klockgether T., Schmidt-Wolf I., Schlegel U. Cognitive performance and magnetic resonance imaging findings after high-dosesystemic and intraventricular chemotherapy for primary central nervous system lymphoma. Arch Neurol. 2003 Apr;60(4):563-8.


Schlegel U., Pels H., Glasmacher A., Kleinschmidt R., Schmidt-Wolf I., Helmstaedter C., Fliessbach K., Deckert M., Van Roost D., Fimmers R., Bode U., Klockgether T. Combined systemic and intraventricular chemotherapy in primary CNS lymphoma: a pilot study. J Neurol Neurosurg Psychiatry. 2001 Jul;71(1):118-22. 


 

Other publications


Hoppe C., Fliessbach K., Stausberg S., Stojanovic J., Trautner P., Elger C.E., Weber B. A key role for experimental task performance: Effects of math talent, gender and performance on the neural correlates of mental rotation. Brain and Cognition. Accepted for publication.

 

Hummel T.*, Fliessbach K.*, Abele M., Okulla T., Reden J., Reichmann H., Wüllner U., Haehner A. Olfactory fMRI in patients with Parkinson’s disease. Front Integr Neurosci. 2010 Oct 28;4:125. *gemeinsame Erstautorenschaft


Linder N.S., Uhl G., Fliessbach K., Trautner P., Elger C.E., Weber B. Organic labeling influences food valuation and choice. Neuroimage. 2010 Oct 15;53(1):215-20.


Montag C., Weber B., Fliessbach K., Elger C.E., Reuter M. The BDNF Val66Metpolymorphism impacts parahippocampal and amygdala volume in healthy humans: incremental support for a genetic risk factor for depression. Psychol Med. 2009Nov;39(11):1831-9.


Weber B., Fliessbach K., Elger C.E. Highly functional ipsilateral motor control after extensive left hemispheric damage during gestation. Neurocase. 2006 Oct;12(5):292-5.

Linnebank M., Moskau S., Farmand S., Fliessbach K., Kolsch H., Bos M., Grothe C., Becker D., Harbrecht U., Pohl C., Wullner U., Klockgether T. Homocysteine and carotid intima-media thickness in a german population: lack of clinical relevance.Stroke. 2006 Nov;37(11):2840-2


Linnebank M., Semmler A., Kleijer W.J., van der Sterre M.L., Gartner J., Fliessbach K., Sokolowski P., Kohler W., Schlegel U., Klockgether T., Wanders R.J., Schmidt S., Wullner U., Kemp S. The cystathionine beta-synthase variant c.844_845ins68 protects against CNS demyelination in X-linked adrenoleukodystrophy. Hum Mutat. 2006 Oct;27(10):1063-4.


Wetter A., Engl T.A., Nadjmabadi D., Fliessbach K., Lehnert T., Gurung J., Beecken W.D., Vogl T.J. Combined MRI and MR spectroscopy of the prostate before radical prostatectomy. AJR Am J Roentgenol. 2006 Sep;187(3):724-30.


Wetter A., Ajdukovic A.N., Fliessbach K., Lehnert T., Engl T., Jacobi V., Vogl T.J. Staging des Prostatakarzinoms: Wertigkeit der kombinierten Information aus endorektaler MRT, bioptischem Gleasn Score und präoperativem PSA-Wert. Röfo. 2006 Apr;178(4):385-90.


Linnebank M., Kemp S., Wanders R.J., Kleijer W.J., van der Sterre M.L., Gartner J., Fliessbach K., Semmler A., Sokolowski P., Kohler W., Schlegel U., Schmidt S., Klockgether T., Wullner U. Methionine metabolism and phenotypic variability in X-linked adrenoleukodystrophy. Neurology. 2006 Feb 14;66(3):442-3.


Weber B., Hoppe C., Faber J., Axmacher N., Fliessbach K., Mormann F., Weis S., Ruhlmann J., Elger C.E., Fernandez G. Association between scalp hair-whorl direction and hemispheric language dominance. Neuroimage. 2006 Apr 1;30(2):539-43.


Linnebank M., Fliessbach K., Kölsch H., Rietschel M., Wüllner U. The methionine synthase polymorphism c.2756→G (D919G) is relevant for disease-free longevity. Int J Mol Med. 2005 Oct;16(4):759-61.


Wetter A., Hubner F., Lehnert T., Fliessbach K., Vorbuchner M., Roell S., Zangos, S., Luboldt W., Vogl T.J. Three-dimensional 1H-magnetic resonance spectroscopy of the prostate in clinical practice: technique and results in patients with elevated prostate-specific antigen and negative or no previous prostate biopsies. Eur Radiol. 2005 Apr;15(4):645-52.


Linnebank M., Pels H., Kleczar N., Farmand S., Fliessbach K., Urbach H., Orlopp K., Klockgether T., Schmidt-Wolf I.G., Schlegel U. MTX-induced white matter changes are associated with polymorphisms of methionine metabolism.Neurology. 2005 Mar 8;64(5):912-3.


Schröder R., Watts G.D., Mehta S.G., Evert B.O., Broich P., Fliessbach K., Pauls K., Hans V.H., Kimonis V., Thal D.R. Mutant valosin-containing protein causes a novel type of frontotemporal dementia.Ann Neurol. 2005 Mar;57(3):457-61.


Linnebank M., Schmidt S., Kolsch H., Linnebank A., Heun R., Schmidt-Wolf I.G., Glasmacher A., Fliessbach K., Klockgether T., Schlegel U., Pels H. The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma. Br J Cancer. 2004 May 17;90(10):1969-71

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